When the Multi Locations feature is enabled, every Connector on your Zedonk is updated with an additional setting field called 'Zedonk Location' that allows you to specify which location you'd like to synchronise with your Connector.
If the external system supports multiple locations (Shopify, JOOR, Lingo EDI, most warehouse connectors), you will require multiple Connectors, one for each location you need to synchronise with an external system.